FDA OKs 1st Embryonic Stem Cell Trial for Geron, Stock Skyrockets

The first clinical human trial using embryonic stem cells as a medical treatment in the United States has been approved by the U.S. Food and Drug Administration. Roughly ten patients will be treated about 2 weeks after they have suffered from acute spinal cord injuries that would normally result in permanent paralysis without the new therapy. The hope is that the stem cell therapy will help the body to heal itself from the spinal cord injury, allowing the patients to regain some or even most of their ability to walk and move.

In a landmark study published in 2005, this same therapy was shown to allow mice who were paralyzed as a result of an acute spinal cord injury to walk again. Should similar results be achieved in these human trials it will represent a major advance in efforts to heal what have historically been devastating and untreatable human injuries.

Geron, the company behind the trials, has a long history as a pioneer in scientific discovery. In 1999 Geron acquired the patents and intellectual property behind Dolly the lamb, the world sensation that was the first mammal to be cloned from an adult somatic cell, using the process of nuclear transfer. (wikipedia). In the stock market today, Geron’s stock price surged in enthusiasm for the FDA approval. (Stock Chart: source). Geron has an entire website dedicated to the announcement which includes this very instructive

Play Video :

So how does this stem cell therapy from Geron work?


Contrary to common perception, stem cells are not what Geron will be injecting into the injured patients. Instead a different type of cells called oligodendrocyte progenitor cells will be derived from stem cells, and it is these progenitor cells that will be injected into the patients. Researchers at Geron are able to coax human embryonic stem cells (hESC) to differentiate into progenitor cells under specific laboratory conditions. According to Geron “these progenitor cells, once placed in the patient, have demonstrated remyelinating and nerve growth stimulating properties leading to restoration of function in animal models of acute spinal cord injury (Journal of Neuroscience, Vol. 25, 2005).”

Officials from Geron are quick to caution against over optimistic expectations. Although the therapy has proven it can allow rats to regain their ability to walk after suffering an acute spinal cord injury, it is yet to be seen what effect this therapy will have on humans. Geron claims that their main objective is to prove the safety of stem cell based therapies, but we don’t it. We all know that Geron is hoping that the therapy will restore motor function in humans similar to that seen in the rat trials.

It should be noted, as we have reported previously, that stem cell treatments outside of the United States have been commonplace for years. At first glance Geron’s work therefore may not seem like a big deal, but this misses the point.

The Geron trials are a major step forward because they are the first ever approved by the FDA, bringing a whole new level of credibility, oversight, and scientific rigor to the field that has been lacking in other trials. Many of the other trials that have occurred outside of the jurisdiction of the FDA, such as those in China, have been ridiculed for having little oversight, questionable practices, and very little peer reviewed, reproducible data. In addition, many argue there is not much science behind these other efforts. The researchers literally seem to be injecting stuff into patients with a “lets see what happens” approach and with little basis of scientific theory. In stark contrast, the science behind Geron’s work has been tested exhaustively in the lab on animals, the mechanism behind its operation is known, the patents backing their work are formidable, and the manufacture of the cells ideally meets strict demands for procedure, sterilization, and so forth.

Stem cell therapies have been a controversial issue in the United States because of ethical concerns surrounding the destruction of embryonic cells. For 8 years President Bush has severely limited the supply of stem cell lines that could be used by researchers and he has put a virtual lock on federal funding for related research. Officials are claiming that it is simply a coincidence that the FDA approved the trials just days after Bush left office and the stem cell friendly Obama stepped in, but is it really a coincidence? We aren’t so sure. In any case, the rise of Obama portends a renewed openness in America for stem cell research and further hastens the coming era of miraculous treatments for the sick and injured.

Source : http://singularityhub.com

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Herm Gets The Hook; Edwards Out As KC Coach

We figured it wouldn’t be a matter of “if”, but “when”. And the “when” turned out to be today. The Kansas City Chiefs have fired Herm Edwards.
Adam Teicher of the KC STAR reports that Herm has been given his walking papers on Friday, thus following the footsteps of so many fellow ex-Jets coaches who get jettisoned from their jobs.
When an “excited” Scott Pioli took the reins as Chiefs GM earlier this month, you would figure some house cleaning would be in order. And Edwards hasn’t done himself any favors by leading KC to a franchise-worst 2-14 last year, while also losing 23 of their last 25 games. We’re talking Detroit Lions loathsome here, folks.
Herm must have forgot to remind his players that they play to win the game. And it’s hard to achieve NFL success when you’re riding on the shoulders of Tyler Thigpen, a QB from Coastal Carolina. (But we kid the Chanticleers, knowing full well that we wouldn’t want to mess with such bad-news boys.)
Now Pioli can get to work perusing resumes of potential replacements. Welcome to KC, Kirk Ferentz?

Source : http://www.sportsbybrooks.com

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DCCC Chairman Chris Van Hollen Condemns Rush Limbaugh’s Comment Hoping President Obama Fails

Condemnation is good, but a joint resolution of Congress admonishing him would be even better.
"Rush Limbaugh's reprehensible remark that he ‘hopes' President Obama fails to meet the extraordinary economic challenges Americas face has no place in the public discourse.

"Mr. Limbaugh's comments politicize the economic struggle of millions of hard working Americans. With the unemployment rate over seven percent, today's news that 62,000 more Americans filed for unemployment benefits last week, and millions of Americans struggling to keep their health care and homes, all Americans, regardless of their ideology, hope that President Obama succeeds in getting people back to work and turning our economy around."

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Obama Scraps Controversial Bush “Mexico City” Abortion Funds Policy

President Barack Obama has moved to scuttle one of former President George Bush’s most controversial anti-abortion actions:

President Barack Obama on Friday struck down the Bush administration’s ban on giving federal money to international groups that perform abortions or provide abortion information — an inflammatory policy that has bounced in and out of law for the past quarter-century. Obama’s executive order, the latest in an aggressive first week reversing contentious Bush policies, was warmly welcomed by liberal groups and denounced by abortion rights foes.

The ban has been a political football between Democratic and Republican administrations since GOP President Ronald Reagan first adopted it 1984. Democrat Bill Clinton ended the ban in 1993, but Republican George W. Bush re-instituted it in 2001 as one of his first acts in office.

A White House spokesman, Bill Burton, said Obama signed the executive order, without coverage by the media, late on Friday afternoon. The abortion measure is a highly emotional one for many people, and the quiet signing was in contrast to the televised coverage of Obama’s Wednesday announcement on ethics rules and Thursday signing of orders on closing the Guantanamo Bay prison camp and banning torture in the questioning of terror suspects.

In its report the AP further notes that this action comes one day after the 36th anniversary of the Roe v. Wade abortion right decision that sparked a furor and created an election winning-losing “wedge” issue. The Washington Post notes that this policy was originally put in place by President Ronald Reagan, then scrapped by President Bill Clinton, and then put back in place by President Bush.

The order rescinds the Mexico City Policy, also known as the “gag rule,” which President Ronald Reagan originally instituted in 1984 and President Bill Clinton rescinded and President George W. Bush revived in 2001.

The decision had been eagerly expected by family planning groups, women’s health advocates and others, who hoped it would restore millions of dollars of funding to programs providing health care, contraceptive services, HIV prevention and other care around the world.

“For eight long years the global gag rule has been used by the Bush administration to play politics with the lives of poor women across the world,” said Gill Greer of the International Planned Parenthood Federation in London. “In rescinding this disastrous and unjust policy, President Obama has returned the United States to the international consensus on women’s health.”

The decision, which came one day after thousands of antiabortion activists participated in a March for Life on the Mall to protest the Roe v. Wade Supreme Court decision legalizing abortion in the United States, was condemned by conservative groups.

“Yesterday, President Obama issued executive orders banning the torture of terrorists but today signed an order that exports the torture of unborn children around the world,” said Tony Perkins of the Family Research Council.

“At a debate last year at Rick Warren’s Saddleback Church, then-candidate Barack Obama vowed to find ‘common ground’ on the issue of abortion and that he, as president, would work to ‘reduce the number of abortions,’ ” Perkins said. “His action today flies in the face of that vow and probably sets a record as the most quickly broken campaign promise ever, leaving the question, how many more broken promises to families lie ahead?”

But Obama had also made it clear he was not in agreement with Bush policies on this issue. What appears to be happening is that Obama is moving swiftly to take actions on some things he can easily do to fulfill some promises to the voters who worked hardest for him (reverse this policy, order Guantanamo closed, call in military leaders to talk about starting a serious process to plan to get out of Iraq, extending olive branches to the GOP even as talk radio hosts and some former Bush aides demonize him).

These are the promises he can keep. There are host of other that likely won’t occur.

So the move is signficant for several reasons:

1. It signals Obama taking full advantage of the honeymoon period to do some image-creating important policy changes from the Bush administration. This can only increase his clout at the beginning of his term.

2. It starts the process to roll back the impact that an anti-abortion-rights federal goverment had on this issue…even though history shows that on this issue the federal government has been like a see-saw.

3. It means Republicans will have a field day in their fund raising as they point to this and other Obama issues to argue to stalwarts that the need big bucks to get into power to roll back what Obama has rolled back.

4. It means Democrats are unlikely to want to lose power over the next 8 years because now they are again getting a taste of what it feels like when they system is on THEIR side.

Source : http://themoderatevoice.com

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Catch Me if You Can (2002) Starring Leonardo DiCaprio, Tom Hanks based on the novel by Frank Abagnale Jr.

Questioning the Story (Fact or Fiction):

Was the FBI Agent played by Tom Hanks a real person?
No, there is no real Carl Hanratty, Tom Hanks revealed in an interview. There was an agent who was Frank's main contact, but a lot of FBI agents helped catch Abagnale.

Did Frank really escape a VC10 jetliner by removing the toilet and climbing down beneath it, eventually escaping through a hatch onto the tarmac?
The event is in Frank's 1981 memoir, but airline experts say it is impossible. "The entire system is sealed," says Skip Jones of the Aerospace Industries Association.
"No matter what happens in there, you can't get into the rest of the airplane." Payload systems engineer Alan Anderson explains that the toilets are mounted on top of tanks that weigh over 100 pounds, and even if he manage to undo the toilet, he would have to crawl through a pipe four inches in diameter. "A person would have to be pretty small, and it would be messy," says Anderson.

Why did he do it?
Only Frank Abagnale, Jr. can answer this question, and in an interview he said the following, "It begins with my parents’ divorce and its dramatic effect on me. I ran away and suddenly found myself a teenager alone in the world. I had to grow up very quickly and become very creative in order to survive. But what started out as survival became more and more of a game. I was an opportunist, so when I saw an opening I asked myself, ‘Could I get away with that?’ Then there was the satisfaction of actually getting away with it. The more I got away with, the more of a game it became—a game I knew I would ultimately lose, but a game I was going to have fun playing until I did."

Leonardo DiCaprio and Frank Abagnale, Jr. (on the set):

"To look at him, you wouldn’t think he could steal a postage stamp. But he has an almost unconscious way of engaging you with his eyes, with his energy and with his intelligence." - Leonardo DiCaprio

Frank Abagnale, Jr. Speaks (watch the interview):

Frank Abagnale Interview

PLAY: video Watch Frank Abagnale Jr. Speaking - SPLYCED, 37:41
Interview runs approx. 37:41 min. Made available thanks to Auto Network.

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Timbuktu, Mali

My eyes popped open, my heart pounded and my body jumped out of bed. It was 4am in Sevare and I could barely contain my excitement, “Wake up boys, We’re going to Timbuktu, we’re going to Timbuktu, we’re going to Timbuku!” This was the day that would finally solidify my status as a world traveler. I wanted to get there…now!
They grudgingly slid out of their beds and fell back into the same positions as they passed out in the car. After two more hours of blissful sleep they were rudely awakened as our car got off the paved road and hit the dirt road. For the next 6 hours, we took the desert by storm, crossing sand roads to Timbuktu, darting dozens of camels, hundreds of donkeys and averting thousands of kilograms of sand we were unavoidably choking on. After an hour, our driver spotted us cleaning up our faces like cats in his rear view mirror, and pulled over laughing. He helped us wrap turbans around our heads that would block the dust and sand from exfoliating our faces, to make the journey up to the mystical city a little more manageable.

After crossing the Niger river, again, we made it to Timbuktu just after lunch time. In typical Kash travel fashion, we dropped off our bags at Hotel Buktu and fled off in a hurry to tour the town before nightfall. No resting allowed. After an hour or so (Timbuktu is not very big), we met our camel guides who happened to be around 7 years old, that took us out to the sandy dunes just outside the city to watch the sunset. Upon returning to our hotel, our teeth were chattering and our speech impeded. IT IS COLD out here at night!

There is not much to see in Timbuktu besides sand and camels, but that’s enough for me. I love the desert! The turbans are also a big plus.

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Obama declares end to "war on terror"

As defined by his predecessor. Obama reassures Muslims yet again. More on this story. "Obama 'declared end' to war on terror: media," from the AFP, January 23:

WASHINGTON (AFP) – President Barack Obama "declared an end" to his predecessor's "war on terror" and began to heal the US reputation abroad when he ordered the Guantanamo Bay prison to close, US editorialists wrote Friday.
Obama's order to close the detention facility within a year, end coercive interrogations and shut secret overseas CIA prisons sent a strong signal to the world and presented a new post-September 11 era, wrote The Washington Post.

"President Obama yesterday eliminated the most controversial tools employed by his predecessor against terrorism suspects," the Post said.

"With the stroke of his pen, he effectively declared an end to the 'war on terror,' as President George W. Bush had defined it, signaling to the world that the reach of the US government in battling its enemies will not be limitless," it said.

"In a broad swipe at the Bush administration's lawyers, Obama nullified every legal order and opinion on interrogations issued by any lawyer in the executive branch after September 11, 2001," the Post added.

"It was a swift and sudden end to an era that was slowly drawing to a close anyway, as public sentiment grew against perceived abuses of government power."...

Source : http://www.jihadwatch.org

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Obama lifts Mexico City Policy (gag rule) prohibition on sending funds to overseas family planning

President Obama signed an executive order today reversing the ban that prohibits funding to international family planning groups that provide abortions, as first reported by ABC News.

Under the hotly debated “Mexico City Policy,” the U.S. government cannot provide funding for family planning services to clinics or groups that offer abortion-related services overseas, even if funding for those activities comes from non-government sources. It essentially bars recipients of U.S. foreign aid from promoting abortion as a method of family planning.

If organizations received government funding, they would “agree as a condition of their receipt of federal funds that such organizations would neither perform nor actively promote abortion as a method of family planning in other nations.”

The policy, dubbed the “Global Gag Rule” by pro-abortion supporters, was introduced by the administration of Ronald Reagan in 1984 in Mexico City, and was instituted that year. It was then overturned by President Bill Clinton in 1993 and restored by George W. Bush at the beginning of his office in 2001.

Source : http://www.writeslikeshetalks.com

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President Obama Orders Pakistan Drone Attacks

A pair of US drone strikes in the North and South Waziristan tribal agencies of Pakistan killed 20 people today. Many of them appear to have been militants, but at least four of them were also children. The attacks, the first of President Obama’s fledgling administration, and the responses in their aftermath suggest that, in the end, very little has changed.

Pakistan has complained, as they always do. Major General Athar Abbas, the spokesman for Pakistan’s military, complained that the Pakistani Army was trying to take action against militants in the tribal area, but the US drone strikes were hindering both the potential offensives and undermining efforts to drive a wedge between the Taliban and the various tribes in the area.

And, as they always did during the Bush Administration, the Obama White House has declined to comment in any way on the attacks. At the swearing in ceremony, the new president complained that there has been too much secrecy in recent days. Yet when the chips are down and US missiles have killed four innocent children, he has become a quick study at the idea of “no comment.”

Source : http://news.antiwar.com

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FDA OKs First Human Trials of Embryonic Stem Cells

The Federal Drug Administration has approved the first human trials of embryonic stem cells — a sign of a new, liberal attitude toward stem cell research, which was hamstrung by the Bush administration.
Starting this summer, the biotech firm Geron will treat a small group of spinal-cord injury patients using neurons derived from stem cells, marking the first time embryonic stem cells will be tested in humans.
The trial is designed to test the safety of the treatment, not how well it works. Nonetheless, it's a huge first step for the field.
"It signals to me that we have the primary regulatory authorities on board for embryonic stem cells," said Alan Trounson, president of the California Institute of Regenerative Medicine, a $3 billion state initiative to support stem cell research. "That really is a tremendous piece of news."

Under the Bush administration, stem cell research was slowed by an executive order, signed in August 2001, that (severely) restricted the types of stem cells and stem cell research that could be conducted. President Barack Obama is widely expected to lift Bush’s executive order, perhaps as soon as next week.
Working in a handful of medical centers around the country, Geron will treat eight to 10 recent paraplegics, who can use their arms but not their legs. The patients will receive an injection of neurons to the site of the damage, followed by a short treatment of anti-rejection drugs.
Previous animal studies suggest the new neurons will repair damaged neurons and secrete substances to help nerves function and grow.
Amy Rick, president of Coalition for the Advancement of Medical Research, a group of dozens of research institutions that support stem cell research, said the Geron trial is a milestone.
"It's hugely significant in the sense that it's the first approval of a human embryonic stem cell trial," she said. "In this week of hope and change, it feels even better."
While Geron scientists waited months for FDA approval of the stem cell treatment, they are reluctant to link the go-ahead directly to the inauguration of Obama.
A Geron spokeswoman said that the company had no evidence of political influence aiding their application.
“It’s just coincidental timing,” the spokeswoman said.
Karen Riley, an FDA spokeswoman, echoed that the timing was coincidental. "We make science-based decisions and politics is not a factor," she said.
But the new president surely didn't hurt matters. The chairman of Trounson's organization told the New York Times, "I think this approval is directly tied to the change in administration."
The approval is expected to the first of several trials involving embryonic stem cells. A recent CAMR report found that nine companies, including Geron, were in the process of developing human embryonic stem cell treatments.
Embryonic stem cells are like blank slates that can be transformed into different types of tissue. They've been hailed as the next big thing in medicine ever since University of Wisconsin scientist James Thomson showed their ability to regenerate in 1998. Since then, stem cells have been like a high school star turned NBA draft pick — talented and expensive but undisciplined and perhaps not quite ready for the glare of the big game. Like many biotechnology techniques, the lag between scientific discovery and clinical treatment can be decades.
Still, the Regenerative Medicine Institute’s Trounson, who was a stem cell scientist in Australia before heading the California institute, said that experimental treatments are outpacing his expectations.
"We're running an agency funding this work and I'm astounded at what's happening in this space,” he said.
Trounson said there’s evidence in animal trials that stem cells are effective in treating ailments as varied as diabetes, Alzheimers, multiple scleorsis and macular degeneration.
“It’s just fantastic,” Trounson said. "And I would expect some of these to enter clinical trials sooner, rather than later."
His agency expects to fund up to a dozen scientists who think they can submit their stem cell work to the FDA for clinical trial approval within four years.
From there, those so-called investigational new drugs will have to follow the path that Geron's treatment did. The company submitted its application early in 2008. It was then put on hold in May 2008 and kicked back to the company for further review. Seven months later, the company resubmitted the application and received approval Wednesday, the day after the inauguration.
That said, Obama's political influence is likely to invigorate a field that — despite impressive state-level and private efforts — has been ham-strung by Federal regulation and the specter of increased government regulation.
"With President Obama there, there will be a big change not only in government administration and the public sector, but I think it will encourage the pharmaceutical companies to be involved as well," Trounson said.
Image: flickr/limowreck666

Source : http://blog.wired.com

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Hamas says it's back in control of the Gaza Strip

GAZA CITY, Gaza Strip (AP) - Bearded Hamas leaders on Friday delivered an envelope with five crisp $100 bills to a veiled woman whose house was damaged during Israel's invasion of Gaza, the first of promised relief payments by the militant group.

In another part of the territory, a bulldozer cleared rubble and filled in a bomb crater where a week before a top Hamas leader had been killed in an Israeli air strike.

Since a truce took hold this week, ending Israel's three-week onslaught, Gaza's Hamas rulers have declared victory and gone out of their way to show they are in control.

They have pledged $52 million of their own funds to help repair lives, the money divvied up by category. The veiled woman received compensation for her two-story home in the northern town of Beit Lahiya.

Hamas, believed to be funded by donations from the Muslim world and Iran, has promised $52 million in emergency relief. This would include $1,300 for a death in the family, $650 for an injury, $5,200 for a destroyed house and $2,600 for a damaged house, he said, adding that these are not yet compensation payments, which Hamas promises will follow.

More than 4,000 houses were destroyed and about 20,000 damaged, according to independent estimates.

"We are in control and we are the winner," Hamas legislator Mushir al-Masri declared this week, after attending the funeral of four Hamas gunmen.

But Israeli strikes destroyed all of Hamas' security compounds and most government buildings. Its top two leaders, strongman Mahmoud Zahar and Gaza Prime Minister Ismail Haniyeh, have not yet appeared in public.

Israel claims to have killed more than 700 Hamas fighters, while the militants say they lost about 280 armed men, the vast majority members of the police force killed in surprise bombings on the first day of the war.

But beyond the losses, Hamas is wrestling with a fateful choice—whether to keep fighting and drive Gaza deeper into poverty and suffering or moderate in exchange for open borders and a measure of stability.

Gaza had buckled under a tight border closure by Israel and Egypt for 19 months, suffering increasing shortages, and the war only heightened the misery.

On Thursday, hundreds lined up with blue gas canisters along the main north-south road, near the town of Deir el-Balah, after word spread that cooking gas was being distributed.

Hamad Abu Shamla, 24, waited for seven hours, only to leave empty-handed. The unemployed carpenter—he lost his job to the blockade—said he last had cooking gas five months ago, and that he, his wife and four children have mostly been living on canned food and bread since then.

He said he had already promised his family a steaming plate of couscous for lunch, and was sad to return home and disappoint them.

"We build our hopes on God," he said, when asked about his future. "We don't know what to do. We are empty-handed ... and we don't know what to do."

Hamas would need huge sums to fund reconstruction—some $2 billion according to first estimates—but the international community for now refuses to funnel the money directly to the militants.

Yet Hamas has rebuffed proposals that it set up a unity government with its moderate West Bank rivals, led by Palestinian President Mahmoud Abbas. It is also cool to demands that Abbas' troops or foreign border monitors be deployed to prevent weapons smuggling into Gaza.

Israel and Egypt, which have kept Gaza's borders closed since Hamas seized the territory by force in June 2007, say they won't open the gates unless Hamas relents.

Before the war, Hamas was able to soften the pain of the blockade because weapons, cash and commercial goods were coming in through hundreds of tunnels under the Gaza-Egypt border. Israel says the shipments included explosives and rockets Hamas has been firing at southern Israel.

Israel bombed many tunnels during the war, though reporters have seen smugglers resume operating in some and rebuild others.

For now, most Gazans seem to rally behind Hamas, united in their anger at Israel, though there are some murmurs of discontent.

"Hamas fought the Israelis. No one else did," said Samir Summad, 66, whose four-story house was damaged during an air strike last week that killed Said Siam, a top Hamas leader.

At the time, Siam was in the house next door, and the massive bomb flattened the building and dug a deep crater into the sandy ground. On Friday, new cinderblocks were already stacked at the scene and a bulldozer pushed aside the remaining rubble.

Summad would not say whether he resented Siam for putting the neighborhood at risk. Siam was visiting a brother at the time of the strike. "If I had known he was there, I would have run away," said Summad, adding that five of his family members were wounded in the attack.

Summad said a government inspector came to his house to assess damage, including blown-out windows

Hamas officials say the need open borders to rebuild Gaza. Yet they are evasive about how they hope to lift the blockade without easing their demands.

Hamas officials scoff at the idea of giving a foothold to Abbas, who has been increasingly sidelined, in part because he was perceived by many people as too soft on Israel during the war.

"We have a legitimate government in Gaza that came through democratic choice," said a Hamas spokesman, Fawzi Barhoum, referring to Hamas crushing victory over Abbas' Fatah movement in 2006 parliament elections.

Yet Hamas is taking a risk by sticking to a hard line that will likely keep Gaza's borders closed. Popular support could erode quickly, since most Gazans have no more reserves to withstand a continued closure.

Even before the war, the vast majority of Gaza's 1.4 million people were poor. The blockade wiped out tens of thousands of job, most factories closed for lack of raw materials and water, power and sewage systems became increasingly erratic.

Shehadeh Shehadeh, 39, a Gaza City pastry chef who learned his trade in Israel a decade ago, said he voted for Hamas in 2006 but said he believes the group must become more pragmatic.

He sold his last black forest cake a month ago and can't bake anymore because he's run out of ingredients available only in Israel. The windows of his apartment were blown out during the war, in an airstrike on the nearby Hamas government complex.

Shehadeh, like many Gazans, would like to see Hamas and Fatah reconcile and wants open borders. "I want to stop and breathe for a bit, and live," he said. "Until when will we keep saying, we want resistance and we want war?"

Source: Breitbart

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